Isotretinoin
In stock
10mg · 20mg
from 41,17 £
In brief
- Isotretinoin at Leader Pharma comes in 10mg and 20mg strengths, with packs of 30, 60, 90, 120 and 180 for each, and orders usually reach UK addresses in 9–21 days.
- Its UK licence covers severe forms of acne, including nodular and conglobate acne, once an adequate course of oral antibacterials and topical therapy has failed.
- Treatment generally starts at 0.5 mg per kg of body weight daily and is adjusted to response; most courses last 16–24 weeks, aiming for a cumulative 120–150 mg/kg.
- Isotretinoin is highly teratogenic, so women who could become pregnant need effective contraception from one month before until one month after treatment, with regular pregnancy tests.
- It is prescribed by or under the supervision of a specialist; low mood or changes in behaviour should be reported at once, and cracked lips and dry eyes are frequent. It is POM in the UK.
Questions and answers about Isotretinoin
I don't have a prescription. Can I buy Isotretinoin at your pharmacy?
In our online pharmacy, you can purchase Isotretinoin without a prescription. We guarantee a seamless purchasing experience by providing access to high-quality medication in an easy and confidential manner.Is it possible that Isotretinoin doesn't work?
Yes, in some cases Isotretinoin may not be effective for treating severe acne. Individual response can vary.Can anyone see the contents of my order?
No, the contents of your order with Isotretinoin are strictly confidential. All orders are securely packaged without any external labelling that could reveal the contents, ensuring absolute discretion. We prioritise the privacy of our customers, and no third party will be informed of the details of your order.What is Isotretinoin and how does it work?
Isotretinoin is a vitamin A derivative used for treating severe acne. It works by reducing oil production in the skin, preventing bacterial growth, and decreasing inflammation, leading to a reduction in acne lesions.Is it legal to use Isotretinoin in the United Kingdom?
Yes, isotretinoin is a prescription-only medicine in the UK; it is legally available when prescribed by a qualified healthcare professional (under the supervision of a consultant dermatologist) for approved medical conditions.Mechanism of action of Isotretinoin
Isotretinoin, a vitamin A derivative, regulates the growth of skin cells, reducing oil production and preventing the formation of acne lesions, leading to improved skin appearance and reduced scarring.How long does it take for Isotretinoin to work?
Isotretinoin typically takes around 4-8 weeks to start showing results, with full effects seen after 4-6 months of continuous treatment.How long does the effect of Isotretinoin last?
The effects of Isotretinoin typically last for several months to a year after completing the treatment course, providing long-lasting relief from severe acne.What are the risks of misuse of Isotretinoin?
Isotretinoin may cause severe birth defects, psychiatric issues, and adverse effects like dry skin, lips, and eyes if misused or taken during pregnancy. Proper medical supervision is crucial for safe usage.How long does Isotretinoin stay in the body?
Isotretinoin is largely cleared from the body within about 4 weeks of stopping treatment, which is why pregnancy must be avoided for at least one month afterwards.Will Isotretinoin show up in a drug test?
Isotretinoin is an oral medication prescribed for acne treatment, and it typically does not show up on standard drug tests.Compatibility of Isotretinoin with other medications
Isotretinoin, a potent acne medication, should be used with caution when combined with certain drugs. Here's a list of medications that may interact with Isotretinoin: - Tetracycline antibiotics - Vitamin A supplements - Birth control pills - St. John's Wort - Corticosteroids - Phenytoin For more detailed information or personalised advice, please consult with our support team.Can one consume alcohol while taking Isotretinoin?
It is best to avoid or limit alcohol while taking isotretinoin, because both can raise blood fats (triglycerides) and affect the liver. Your doctor can offer personalised advice based on your overall health and blood test results.Recommended storage method for Isotretinoin
Isotretinoin should be stored below 25°C, away from light, heat, and moisture. Keep it tightly closed in the original container.- Store below 25°C.
- Keep away from light, heat, and moisture.
- Keep tightly closed in the original container.
How should Isotretinoin be taken and in what dosage?
Isotretinoin should be taken with food, once or twice daily as prescribed. Take exactly as directed - do not increase the dose or take it more frequently. How to take:- Take with food
- Follow dosage instructions
- Do not crush or chew capsules
| Dosage form | Directions |
|---|---|
| Capsules | Swallow whole with water or milk, do not crush or chew. |
Can Isotretinoin be taken for an extended period?
Isotretinoin is typically prescribed for a course of 4-6 months, and extended use beyond this period is generally not recommended due to potential side effects.Overdose of Isotretinoin and what to do in case of an overdose
An overdose of Isotretinoin can be harmful, so it is important to seek medical assistance promptly. If you suspect an overdose, you should:- Contact your doctor or NHS 111 immediately for professional advice, or call 999 in an emergency.
- Closely follow the instructions from your healthcare provider.
- Avoid taking additional doses without consulting a doctor.
Comparison of Isotretinoin with other analogues
Isotretinoin is a potent oral retinoid used to treat severe acne. It differs from topical retinoids like adapalene (Differin) and tretinoin, which are applied to the skin. Isotretinoin is also distinct from combination products like Epiduo (adapalene + benzoyl peroxide) and Duac (clindamycin + benzoyl peroxide) and from antibiotics like clindamycin.| Medicine | Description |
|---|---|
| isotretinoin | isotretinoin |
| roaccutane | isotretinoin |
| differin | adapalene |
| epiduo | adapalene + benzoyl peroxide |
| clindamycin | clindamycin |
| dapsone | dapsone |
| duac | clindamycin + benzoyl peroxide |
What you should know before taking Isotretinoin
Before taking Isotretinoin, consult a doctor, avoid alcohol, discuss potential side effects like dry skin and lips, and understand the medication's impact on birth control requirements for women.Contraindications for the use of Isotretinoin
Isotretinoin is a potent medication used for treating severe acne. However, it has several contraindications, including pregnancy, breastfeeding, liver disease, and hypervitaminosis A. It is crucial to discuss your medical history with your healthcare provider before starting this treatment. Contraindications for Isotretinoin: - Pregnancy - Breastfeeding - Liver disease - Hypervitaminosis A - Hypersensitivity to the medication or its components - Certain blood disorders - Severe depression or mental illnessPossible side effects of Isotretinoin
Isotretinoin is an effective treatment for severe acne, but it can cause side effects. The most common side effects include:- Dry skin and lips
- Nosebleeds
- Muscle or joint pain
- Increased sensitivity to sunlight
- Mood changes or depression
Lifestyle: diet and physical activity
Isotretinoin can affect diet and physical activity; consult a doctor for proper guidance to maintain a healthy lifestyle during treatment.How does mental state affect the effectiveness of Isotretinoin
Isotretinoin's effectiveness can be influenced by mental state, as stress, anxiety, and depression may potentially impact treatment adherence and outcomes. However, most individuals tolerate the medication well when closely monitored.When should one consult a doctor?
When taking Isotretinoin, it's advisable to consult a doctor regularly for monitoring and addressing any side effects. Seek medical attention if you experience severe dryness, headaches, vision problems, or unusual bleeding. Regular check-ups help ensure the treatment is effective and safe for you.In which cities can Isotretinoin be delivered?
Isotretinoin is available for delivery in the following cities in the United Kingdom:| City | Region | Delivery Time |
|---|---|---|
| London | Greater London | 9–21 days |
| Birmingham | West Midlands | 9–21 days |
| Manchester | North West England | 9–21 days |
| Liverpool | North West England | 9–21 days |
| Leeds | Yorkshire and the Humber | 9–21 days |
| Glasgow | Scotland | 9–21 days |
| Newcastle upon Tyne | North East England | 9–21 days |
| Sheffield | Yorkshire and the Humber | 9–21 days |
| Bristol | South West England | 9–21 days |
| Edinburgh | Scotland | 9–21 days |
| Belfast | Northern Ireland | 9–21 days |
| Cardiff | Wales | 9–21 days |
