Buy Allopurinol online in the United Kingdom without prescription 🇬🇧 | Leader Pharma Skip to content
Basket 0

Your basket is empty.

View basket
☰

Allopurinol

Allopurinol
In stock
300mg
from 28,23 £
Strength
Pack size — the bigger the pack, the cheaper the tablet
33,88 £ 28,23 £
0,94 £ per tablet

In brief

Allopurinol lowers uric acid production by inhibiting the enzyme xanthine oxidase. It is used for long-term gout prevention rather than immediate relief of pain during an attack.

Questions and answers about Allopurinol

I don't have a prescription. Can I buy Allopurinol at your pharmacy?

In our online pharmacy, you can purchase Allopurinol without a prescription. We guarantee a seamless purchasing experience by providing access to high-quality medication in an easy and confidential manner.

Is it possible that Allopurinol doesn't work?

Allopurinol may not work effectively for some individuals due to factors like drug interactions, kidney function, or genetic variations.

Can anyone see the contents of my order?

No, the contents of your order with Allopurinol are strictly confidential. All orders are securely packaged without any external labelling that could reveal the contents, ensuring absolute discretion. We prioritise the privacy of our customers, and no third party will be informed of the details of your order.

What is Allopurinol and how does it work?

Allopurinol is a medication used to treat gout and kidney stones. It works by decreasing the production of uric acid in the body, which helps prevent the buildup of uric acid crystals that cause gout attacks and kidney stone formation.

Is it legal to use Allopurinol in the United Kingdom?

Yes. Allopurinol is a prescription-only medicine (POM) in the United Kingdom, used for the treatment of gout and other conditions when prescribed by a qualified healthcare professional.

Mechanism of action of Allopurinol

Allopurinol is a xanthine oxidase inhibitor that blocks the conversion of purines into uric acid, reducing uric acid levels and preventing the formation of uric acid crystals in the body, thereby treating and preventing gout and other conditions associated with hyperuricaemia.

How long does it take for Allopurinol to work?

Allopurinol typically takes 2-6 weeks to start lowering uric acid levels effectively. However, some patients may experience improvement within a few days.

How long does the effect of Allopurinol last?

Allopurinol is a long-term medication, and its effects typically last as long as you continue taking it regularly as prescribed by your doctor.

What are the risks of misuse of Allopurinol?

Allopurinol misuse can lead to severe side effects like skin rashes, nausea, vomiting, and in rare cases, potentially life-threatening hypersensitivity reactions. Consulting a doctor before use is crucial.

How long does Allopurinol stay in the body?

Allopurinol itself has a short half-life of about 1–2 hours, but its active metabolite oxipurinol has a half-life of approximately 13 to 30 hours, so it can take several days to be fully eliminated from the system.

Will Allopurinol show up in a drug test?

Allopurinol will not typically show up on standard drug tests as it is a prescription medication used to treat gout and kidney stones.

Compatibility of Allopurinol with other medications

Allopurinol may interact with: - Azathioprine and mercaptopurine (their doses must be reduced) - Ciclosporin - Blood thinners (warfarin) - Diuretics (hydrochlorothiazide, furosemide) - Certain antibiotics (ampicillin, amoxicillin) Contact our support team for more details about drug interactions.

Can one consume alcohol while taking Allopurinol?

Alcohol, especially beer and spirits, can raise uric acid levels and trigger gout attacks, so it is best kept to a minimum while taking allopurinol. Your doctor or pharmacist can offer personalised advice.

Recommended storage method for Allopurinol

  1. Store Allopurinol tablets at room temperature, away from heat, moisture, and direct light.
  2. Keep the medication in its original container, tightly closed.
  3. Do not store Allopurinol in the bathroom or near a sink.
  4. Discard any unused medication after the expiry date.

How should Allopurinol be taken and in what dosage?

Allopurinol should be taken orally, with or without food, as directed by your doctor. The usual starting dose is 100 mg once daily, increased gradually according to blood uric acid levels; maintenance doses are usually 100–600 mg daily. Here's how to take it:

How to take
- Swallow the tablets whole with a glass of water
- Take the medication at the same time each day
- Follow your doctor's instructions carefully

Can Allopurinol be taken for an extended period?

Yes, Allopurinol can be taken for an extended period to manage chronic gout or kidney stone conditions under medical supervision.

Overdose of Allopurinol and what to do in case of an overdose

An overdose of Allopurinol can be harmful, so it is important to seek medical assistance promptly. If you suspect an overdose, you should:
  • Contact your doctor or NHS 111 immediately for professional advice, or call 999 in an emergency.
  • Closely follow the instructions from your healthcare provider.
  • Avoid taking additional doses without consulting a doctor.
Remember, prompt action is crucial.

Comparison of Allopurinol with other analogues

MedicineDescription
allopurinolallopurinol
febuxostatfebuxostat
colchicinecolchicine
probenecidprobenecid
lesinuradlesinurad
sulfinpyrazonesulfinpyrazone
benzbromaronebenzbromarone
Allopurinol is a xanthine oxidase inhibitor that lowers uric acid levels in the body. Compared to other analogues like febuxostat, lesinurad, and benzbromarone, which also target uric acid production/excretion, allopurinol is generally considered the first-line treatment for chronic gout due to its efficacy and safety profile.

What you should know before taking Allopurinol

Allopurinol requires regular blood tests, can cause side effects like rash, nausea, and liver issues, and should be avoided with certain medications and medical conditions. Consult your doctor for safe usage.

Contraindications for the use of Allopurinol

Allopurinol is generally well tolerated, but it must not be used by people with hypersensitivity to the drug, and it should not be started during an acute gout attack. Doses are reduced in kidney or liver impairment, and in pregnancy it is used only if there is no safer alternative. Caution is advised when used with other medications like azathioprine, cyclophosphamide and mercaptopurine.

Possible side effects of Allopurinol

Allopurinol is a medication used to treat gout and kidney stones. While generally well-tolerated, it may cause some side effects:
  • Rash or skin irritation
  • Nausea or vomiting
  • Diarrhoea
  • Headache
  • Dizziness
Most side effects are mild and go away with continued use. However, seek medical attention if you experience severe side effects.

Lifestyle: diet and physical activity

Allopurinol can be beneficial for managing gout, which is often associated with dietary and lifestyle factors, but it should be taken as prescribed by a healthcare professional.

How does mental state affect the effectiveness of Allopurinol

Allopurinol's effectiveness can be influenced by a person's mental state, as stress, anxiety, and depression may affect medication adherence and overall well-being, potentially impacting the drug's ability to manage uric acid levels effectively.

When should one consult a doctor?

When taking allopurinol, it's important to consult a doctor if you experience any side effects, such as rash, fever, joint pain, or difficulty breathing. Additionally, regular blood tests may be required to monitor your uric acid levels and kidney function. Seek medical advice before starting or stopping this medication.

In which cities can Allopurinol be delivered?

Allopurinol is available for delivery in the following cities in the United Kingdom:
City Region Delivery Time
London Greater London 9–21 days
Birmingham West Midlands 9–21 days
Manchester North West England 9–21 days
Liverpool North West England 9–21 days
Leeds Yorkshire and the Humber 9–21 days
Glasgow Scotland 9–21 days
Newcastle upon Tyne North East England 9–21 days
Sheffield Yorkshire and the Humber 9–21 days
Bristol South West England 9–21 days
Edinburgh Scotland 9–21 days
Belfast Northern Ireland 9–21 days
Cardiff Wales 9–21 days
For additional locations and delivery enquiries, please contact our support team.

Related products