Methotrexate

Methotrexate

Dosage
2,5mg
Package
120 pill 90 pill 60 pill 30 pill
Total price: 0.0
  • In our pharmacy, you can buy Methotrexate without a prescription, with delivery in 5–14 days throughout US. Discreet and anonymous packaging.
  • Methotrexate is an antineoplastic and immunomodulating agent used to treat certain cancers, autoimmune diseases (like rheumatoid arthritis), and severe psoriasis. It works by inhibiting folic acid metabolism, disrupting DNA synthesis in rapidly dividing cells.
  • The usual weekly dose ranges from 7.5 mg to 25 mg for non-cancer indications. Higher doses are used for oncology. Available in tablets (2.5-15 mg), oral solutions (2-2.5 mg/ml), or injections (10-25 mg/ml).
  • Administration forms include oral tablets, oral solution (e.g., Jylamvo, Xatmep), and injections (subcutaneous/intramuscular via autoinjectors like Otrexup/Rasuvo, or intravenous via vials).
  • Absorption begins within 1–2 hours after oral administration, but therapeutic effects for chronic conditions may take 3–6 weeks to become noticeable.
  • Duration of action varies by dose. Low doses (e.g., for arthritis/psoriasis) require weekly dosing due to prolonged intracellular effects and slow elimination.
  • Strictly avoid alcohol consumption, as it significantly increases the risk of liver toxicity when combined with Methotrexate.
  • The most common side effects include nausea, mouth sores, fatigue, and increased susceptibility to infections.
  • Would you like to try Methotrexate without a prescription?
Trackable delivery 5-9 days
Payment method Visa, Mastercard, Discovery, Bitcoin, Ethereum
Free delivery (by Standard Airmail) on orders over £150

Description of Methotrexate

Active Ingredient Methotrexate
Packaging Type tablet
Quantity per Package 30-360
Price of Methotrexate From EUR 1,12 per tablet
Dosage 10mg-2.5mg
Sale of Methotrexate without prescription

Questions and Answers about Methotrexate

I don't have a prescription. Can I buy Methotrexate at your pharmacy?

In our online pharmacy, you can purchase Methotrexate without a prescription. We guarantee a seamless purchasing experience by providing access to high-quality medication in an easy and confidential manner.

Is it possible that Methotrexate doesn't work?

Methotrexate may not be effective for some individuals, as every person's response to medication can vary.

Can anyone see the contents of my order

No, the contents of your order with Methotrexate are strictly confidential. All orders are securely packaged without any external labeling that could reveal the contents, ensuring absolute discretion. We prioritize the privacy of our customers, and no third party will be informed of the details of your order.

What is Methotrexate and how does it work?

Methotrexate is an anticancer medication used to treat certain types of cancer and autoimmune diseases. It works by inhibiting the production of folic acid, essential for cell growth and division, thus slowing or stopping the growth of cancer cells and reducing inflammation.

Is it legal to use Methotrexate in United Kingdom?

Methotrexate is a prescription medication legally available in the United Kingdom when prescribed by a licensed healthcare professional for approved medical conditions.

Mechanism of action of Methotrexate

Methotrexate is an antimetabolite that inhibits dihydrofolate reductase, an enzyme involved in the synthesis of purine and pyrimidine nucleotides, leading to the inhibition of DNA synthesis and cell division, thereby exhibiting cytotoxic effects on rapidly dividing cells.

How long does it take for Methotrexate to work?

Methotrexate typically takes 3-6 weeks to start working for conditions like rheumatoid arthritis or psoriasis. However, individual response times may vary.

How long does the effect of Methotrexate last?

Methotrexate's effect typically lasts 3-6 months after stopping treatment, making it a long-lasting medication option.

What are the risks of misuse of Methotrexate?

Misuse of Methotrexate can lead to serious side effects like liver damage, suppressed immune system, and birth defects. Proper medical supervision is crucial for safe usage.

How long does Methotrexate stay in the body?

Methotrexate typically stays in the body for around 3 to 10 hours, depending on the dosage and individual factors.

Will Methotrexate show up in a drug test?

Methotrexate, a medication used to treat certain cancers and autoimmune diseases, may potentially show up in some drug tests as a false positive for substances like opioids or certain illegal drugs.

Compatibility of Methotrexate with other medications

Methotrexate, a powerful medication, has potential interactions with: - NSAIDs (e.g., ibuprofen, naproxen) - Certain antibiotics (e.g., trimethoprim-sulfamethoxazole) - Proton pump inhibitors (e.g., omeprazole) - Sulfonylureas (e.g., glyburide) - Theophylline For comprehensive guidance, please consult our knowledgeable support team.

Can one consume alcohol while taking Methotrexate?

Although moderate alcohol consumption is generally not prohibited when taking Methotrexate (Methotrexate), it's always best to consult your healthcare provider. They can offer personalized advice based on your overall health condition, medication dosage, and potential risks of interactions.

Recommended storage method for Methotrexate

  1. Store Methotrexate at room temperature between 20°C to 25°C (68°F to 77°F).
  2. Keep the medication in its original container, tightly closed, and away from moisture and direct sunlight.
  3. Do not freeze or refrigerate unless directed by a healthcare professional.

How should Methotrexate be taken and in what dosage?

Methotrexate is typically taken once a week, either as a pill or injection. The dosage can range from 7.5 mg to 25 mg per week, depending on the condition being treated and other factors.
How to Take Methotrexate
- Take it exactly as prescribed by your doctor
- Swallow the pill whole with water or inject it into the muscle/under the skin
- Take it on the same day each week
- Do not skip or change the dose without consulting your doctor

Can Methotrexate be taken for an extended period?

Methotrexate can often be taken long-term, but regular monitoring by a healthcare professional is important to manage potential side effects and risks.

Overdose of Methotrexate and what to do in case of an overdose

In the rare event of an overdose of Methotrexate, it is generally not considered potentially fatal. However, it's important to seek appropriate medical assistance. If you suspect an overdose, you should:
  • Contact your doctor immediately for professional advice.
  • Closely follow the instructions from your healthcare provider.
  • Avoid taking additional doses without consulting a doctor.
Remember, prompt action is crucial for effectively managing the situation without unnecessary alarms.

Comparison of Methotrexate with other analogs

Methotrexate, also known by various brand names such as Trexall, Otrexup, Rasuvo, Rheumatrex, Jylamvo, Xatmep, Metoject, MTX, and Methoblastin, is an analog of folic acid used as an anticancer and anti-rheumatic drug.
MedicineDescription
methotrexatemethotrexate
trexallmethotrexate
otrexupmethotrexate
rasuvomethotrexate
rheumatrexmethotrexate
jylamvomethotrexate
xatmepmethotrexate
metojectmethotrexate
mtxmethotrexate
methoblastinmethotrexate

What you should know before taking Methotrexate

Methotrexate is a powerful medication that requires monitoring for potential side effects such as liver damage, lung problems, and low blood cell counts. Consult your doctor before starting and while taking this drug.

Contraindications for the use of Methotrexate

Methotrexate should not be taken by pregnant or breastfeeding women, individuals with severe liver or kidney disease, active infections, or impaired immune systems. Contraindications include alcohol abuse, bone marrow suppression, and hypersensitivity to the drug. It is crucial to discuss all medical conditions and medications with a healthcare professional before starting methotrexate. List of contraindications: Pregnancy, breastfeeding, severe liver or kidney disease, active infections, impaired immunity, alcohol abuse, bone marrow suppression, and drug hypersensitivity.

Possible side effects of Methotrexate

Methotrexate, a commonly prescribed medication, can have several potential side effects. These include mouth sores, nausea, fatigue, and an increased risk of infections. More severe side effects may involve liver damage, lung problems, and low blood cell counts. Here's a list of possible side effects:
  • Mouth sores
  • Nausea
  • Fatigue
  • Increased risk of infections
  • Liver damage
  • Lung problems
  • Low blood cell counts

Lifestyle: diet and physical activity

Methotrexate, a medication used for certain conditions, may impact diet and physical activity, requiring monitoring and adjustments for optimal health.

How does mental state affect the effectiveness of Methotrexate

Mental state can influence the effectiveness of Methotrexate. Stress, anxiety, and depression may potentially reduce the drug's efficacy, while a positive mindset and good mental health support optimal treatment outcomes.

When should one consult a doctor?

It is recommended to consult a doctor before starting methotrexate treatment. During treatment, seek medical advice if you experience any unusual side effects or if your condition worsens. Regular checkups are essential for monitoring your health and adjusting the dosage as needed. Always follow your doctor's instructions for safe and effective use.

What is the lowest price for Methotrexate?

In our pharmacy, Methotrexate is available at the most competitive price, ensuring you the best value compared to other suppliers. While other stores may offer quality, our exclusive deals ensure you get premium medication without overpaying. Buy from us and experience the perfect blend of affordability and reliable quality.

In which cities can Methotrexate be delivered?

Methotrexate is available for delivery in the following cities in the United Kingdom:
City Region Delivery Time
London Greater London 5-7 days
Birmingham West Midlands 5-7 days
Manchester North West England 5-9 days
Liverpool North West England 5-9 days
Leeds Yorkshire and the Humber 5-9 days
Glasgow Scotland 5-9 days
Newcastle upon Tyne North East England 5-9 days
Sheffield Yorkshire and the Humber 5-9 days
Bristol South West England 5-9 days
Edinburgh Scotland 5-9 days
Belfast Northern Ireland 5-9 days
Cardiff Wales 5-9 days
For additional locations and delivery inquiries, please contact our support team.